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ACC 2026

Dr. Hyo-Soo Kim and Dr. C. Michael Gibson Discuss: 10-year Follow-up of Clopidogrel Vs Aspirin Monotherapy in Stable Coronary Artery Disease After Percutaneous Coronary Intervention With Drug-eluting Stent View Video View Slides

Dr. Michael Kleiner Shochat and Dr. C. Michael Gibson Discuss: Lung Impedance-Guided Therapy in Heart Failure With Preserved Ejection Fraction: Results of a Randomized Clinical Trial View Video View Slides

Dr. Joost Daemen and Dr. C. Michael Gibson Discuss: Fractional Flow Reserve or 3d-quantitative Coronary Angiography-Based Vessel-Ffr Guided Revascularization – The Fast Iii Trial View Video View Slides


Dr. William Fearon and Ajay Kirtane and Dr. C. Michael Gibson Discuss: A Large-Scale, Global Randomized Trial of Coronary Physiology Derived From Conventional Angiography Compared With An Invasive Pressure Wire-Based Approach to Guide Percutaneous Coronary Intervention View Video View Slides

Dr. Divaka Perera and Dr. C. Michael Gibson Discuss: Controlled Trial of High-Risk Coronary Intervention With Percutaneous Left Ventricular Unloading (CHIP-BCIS3) View Video View Slides

Dr. Stephen Juraschek and Dr. C. Michael Gibson Discuss: DASH-Patterned Groceries to Reduce Blood Pressure Among Adults With Treated Hypertension: Results From the GoFreshRx Randomized Clinical Trial View Video View Slides

Dr. Byeong-Keuk Kim and Dr. C. Michael Gibson Discuss: Intensive Low-Density Lipoprotein Cholesterol Targeting in Patients With Atherosclerotic Cardiovascular Disease View Video View Slides

Dr. Luke Laffin and Dr. C. Michael Gibson Discuss: Kardinal: A Phase 2 Study of Tonlamarsen For the Treatment of Uncontrolled Hypertension View Video View Slides

Dr. Deepak Bhatt and Dr. C. Michael Gibson Discuss: Prevalence and Clinical Impact of Hypercortisolism in Individuals With Resistant Hypertension: Primary Results From the Momentum Study View Video View Slides

Dr. Lohendran Baskaran and Dr. C. Michael Gibson Discuss: Reliability of CAC=0 to Exclude Coronary Plaque in Diverse Global Cohorts: A Global Probability Study of Coronary Artery Disease (GPS-CAD) Analysis View Video View Slides

Dr. Steven Nissen and Dr. C. Michael Gibson Discuss: Effects of Tirzepatide Compared With Dulaglutide on Expanded Cardiorenal Outcomes View Video View Slides

Dr. Harmony Reynolds and Dr. C. Michael Gibson Discuss: Coronary Optical Coherence Tomography and Cardiac Magnetic Resonance Imaging to Determine Sex Differences in Underlying Causes of Myocardial Infarction With No Obstructive Coronary Arteries View Video View Slides

Dr. Pam Taub and Dr. C. Michael Gibson Discuss: Impact of Ivabradine on Orthostatic Intolerance, Quality of Life and Heart Rate in Post-Covid Postural Orthostatic Tachycardia Syndrome: Results From the Recover-Autonomic Trial View Video View Slides

Dr. Samit Shah and Dr. C. Michael Gibson Discuss: A Prospective Multicenter Registry to Define Coronary Vasomotor Disorders in Ischemia With Nonobstructive Coronary Arteries: Primary Results of Discover Inoca View Video View Slides

Dr. Navin Kapur and Dr. C. Michael Gibson Discuss: Primary Left Ventricular Unloading in Anterior ST-Segment Elevation Myocardial Infarction (STEMI) Without Cardiogenic Shock: Results From the STEMI-Door to Unload Randomized Clinical Trial View Video View Slides

Dr. Saibal Kar and Dr. C. Michael Gibson discuss: Outcomes in Patients With Atrial Fibrillation Randomized to Receive Left Atrial Appendage Closure or Oral Anticoagulation: Primary Results of the CHAMPION-AF Clinical Trial View Video View Slides
This Week in Medicine

Dr. Frank Harrell and Dr. C. Michael Gibson talk about the FDA’s new draft guidance on using Bayesian methods in clinical trials—and it could be a game changer. View Vides

Dr. Roger Blumenthal and Dr. C. Michael Gibson review top take away messages from the new lipid guidelines View Video View Slides
This Week in Obesity

Dr. Shantanu Gaur talks with Dr. C. Michael Gibson about the Allurion Smart Capsule, how it works and why it’s gaining attention as a new tool for weight loss and metabolic health. View Video
This Week in Medicine

Dr. Will Gibson and Dr. C. Michael Gibson discuss how p53 was once considered an undruggable target for cancer therapy. View Video

Dr. Nihar Desai and Dr. C. Michael Gibson discuss how practice is moving toward View Video

Dr. Ola Akinboboye and Dr. C. Michael Gibson discuss his recent publication showing that acoramidis has similar efficacy in wild-type and variant transthyretin amyloid cardiomyopathy View Video

Dr. Nick Nurmohamed and Dr. C. Michael Gibson discuss the new concept of Staging Atherosclerosis, where the type (high risk fatty) and the extent of both obstructive and non-obstructive atherosclerosis in the coronary wall is classified as 0-4 (rather than just saying narrowings are present) and how this improves risk stratification. View Video

Dr. Brittany Weber and Dr. C. Michael Gibson discuss: Why Atherosclerosis is All That Really Matters: A Summary for Seamless Integration into Daily Clinical Practice View Video

Dr. Mike Sharma and Dr. C. Michael Gibson discuss the results of the phase III OCEANIC-STROKE Trial: In secondary stroke prevention the Factor Xi inhibitor Asundexian reduced the risk of recurrent ischemic stroke at 1 year by 26%. The absolute reduction was such that only 53 people would we need to be treated to prevent another stroke at 1 year. View Video View Slides

Dr. Roxana Mehran and Dr. C. Michael Gibson discuss: Unmet Needs in Coronary Atherosclerosis: A Discussion of Clinical Trial Designs for Evaluation of Asymptomatic and Symptomatic Patients View Video

Dr. Ahmed and Dr. C. Michael Gibson discuss the neural, autonomic, and inflammatory pathways linking mental health to cardiovascular events View Video

Dr. Karim Al-Azizi and Dr. C. Michael Gibson discuss: Caveat Emptor: Advantages and Disadvantages of Current Generation Tools for Evaluation of Coronary Atherosclerosis View Video

Dr. Malissa Wood and Dr. C. Michael Gibson discuss our personal stories and how CCTA can shift the trajectory of patient management View Video

Dr. Allen Taylor and Dr. C. Mihcael Gibson discuss how Heartflow’s Plaque Analysis AI is changing preventative cardiology, risk stratification, and patient management today in practice View Video

Dr. Christie Ballantyne and Dr. C. Michael Gibson talk about the LDL lowering with an oral PCSK9 inhibitor in patients with familial heterozygous hypercholesterolemia View Video

Dr. Fatima Rodriguez and Dr. C. Michael Gibson discuss: A Proposed Stepwise Approach to Evaluation, Treatment and Tracking of Coronary Atherosclerosis View Video
AHA 2025

Dr. Sripal Bangalore and Dr. C. Michael Gibson discuss the TUXEDO-2 trial: Ticagrelor versus Prasugrel in Patients with Diabetes Mellitus and Multivessel Coronary Artery Disease Undergoing Percutaneous Coronary Intervention View Video | View Slides

Dr. Nicole Cyrille Superville and Dr. C. Michael Gibson discuss: Demographic Disparities in Tafamidis Treatment and Clinical Outcomes Across the United States View Video

Dr. Ann Marie Navar and Dr. C. Michael Gibson discuss the CORAL Reef Study: A new novel, oral PCSK9 inhibitor significantly reduces LDL-C. View Video

Dr. Sandesh Dev and Dr. C. Michael Gibson discuss: Geographic Disparities in Transthyretin Amyloid Cardiomyopathy Prevalence in United States Veterans. View Video

Dr. Jim Januzzi and Dr. C. Michael Gibson discuss: Acoramidis Lowers NT-proBNP in a Larger Proportion of ATTRibute-CM Study Participants with Transthyretin Amyloid. View Video

Dr. Shamir Mehta and Dr. C. Michael Gibson discuss the findings of IPD meta-analysis from Complete Revascularization Trialists’ Collaboration: Does complete revasc reduce CV death or new MI compared to culprit-only PCI when considering the totality of RCT data? View Video | View Slides

Dr. Stephen Nicholls and Dr. C. Michael Gibson Discuss: SURPASS-CVOT — Once-weekly Tirzepatide versus Dulaglutide for Heart Failure Outcomes in Patients with Type 2 Diabetes, ASCVD, and History of Heart Failure (pre-specified analysis of the SURPASS-CVOT Randomized Clinical Trial) View Video | View Slides

FOOD-HF- Examining the Impact of Medically Tailored Meals vs Produce Supplements Delivered Conditionally vs Unconditionally in Heart Failure Readmissions and Emergency Department Visits: A Randomized Clinical Trial View Video | View Slides

Dr. William F Fearon and Dr. C. Michael Gibson Discuss: CAVIAR- Cardiac Allograft Vasculopathy Inhibition with AliRocumab: The CAVIAR Trial View Video | View Slides

POLY-HF – A Polypill Strategy for Heart Failure with Reduced Ejection Fraction: The POLY-HF Trial View Video | View Slides

Dr. Colin Berry and Dr. C. Michael Gibson Discuss: CorCMR – Non-Invasive Endotyping in Patients with Angina and No Obstructive Coronary Artery Disease: A Randomized, Controlled Trial View Video | View Slides

Dr. C. Michael Gibson and Dr. Ginger Jiang Discuss: Zalunfiban at First Medical Contact in Patients with ST-Segment Elevation Myocardial Infarction View Video | View Slides | View Presentation

Dr. Stephen Juraschek and Dr. C. Michael Gibson discuss the GoFresh trial: Can home-delivered, dietitian-assisted DASH groceries reduce BP vs. self-directed grocery shopping for Black hypertensive residents in urban food deserts? View Video | View Slides | View Publication

Dr. John A Dodson and Dr. C. Michael Gibson Discuss: BETTER-BP- Primary results of the Behavioral Economics Trial to Test Effective Regulation of Blood Pressure View Video | View Slides

Dr. Göran Bergström and Dr. C. Michael Gibson discuss the SCAPIS study: Does coronary CT angiography add value beyond calcium score for predicting coronary events? View Video | View Slides | View Publication

Dr. Christopher X Wong and Dr. C. Michael Gibson Discuss: DECAF – The Does Eliminating Coffee Avoid Fibrillation (DECAF) Trial View Video | View Slides

Dr. Amrish Deshmukh and Dr. C. Michael Gibson Discuss: META-AF – Metformin as an Adjunctive Therapy to Catheter Ablation of Atrial Fibrillation View Video | View Slides

Dr. Kevin Alexander and Dr. C Michael Gibson discuss: Acoramidis Effect on All-Cause Mortality in Patients with p.V142I (V122I) Variant ATTR-CM: Findings From the ATTRibute-CM Study View Video

Dr. Atul Verma and Dr. C. Michael Gibson Discuss: OCEAN – The Need for Ongoing Oral Anticoagulation in Patients with Clinical Stroke Risk Factors After Successful Catheter Ablation of Atrial Fibrillation: The OCEAN Randomized Trial View Video | View Slides

Dr. Ulf Landmesser and Dr. C. Michael Gibson Discuss: CLOSURE-AF – Left atrial appendage CLOSURE in patients with Atrial Fibrillation at high risk of stroke and bleeding compared to medical therapy View Video

Dr. Yohei Sotomi and Dr. C. Michael Gibson Discuss: OPTIMA-AF Trial – Short Dual Antithrombotic Therapy after PCI in Patients with Atrial Fibrillation: OPTIMA-AF trial View Video | View Slides

Dr. Jung-Sun Kim and Dr. C. Michael Gibson Discuss: ADAPT AF-DES – Appropriate Duration of Antiplatelet and Thrombotic Strategy after 12 Months in Patients with Atrial Fibrillation Treated with Drug-Eluting Stents View Video | View Slides

Dr. Mary McDermott and Dr. C. Michael Gibson discuss the PERMET trial: Can metformin improve walking performance in nondiabetic patients with peripheral artery disease? View Video | View Slides| View Publication

Dr. Jeffrey I Weitz and Dr. C. Michael Gibson Discuss: ROXI~ Two Mechanistically Distinct Factor XI Antibodies, REGN9933 and REGN7508, for the Prevention of Venous Thromboembolism After Knee Arthroplasty: the ROXI-VTE-I and ROXI-VTE-II trials View Video | View Slides

Dr. Paul Burton and Dr. C. Michael Gibson Discuss: Effect of Evolocumab in Patients at High Cardiovascular Risk without Prior Myocardial Infarction or Stroke: Primary Results of the VESALIUS-CV trial View Video View Slides
This Week in Medicine

Dr. Pam Taub and Dr. C. Michael Gibson discuss: Effects of Lifestyle and Medical Therapy on Changes in Coronary Atherosclerosis: Tracking Plaque for Personalized Medicine View Video
TCT 2025

Dr. Christian M. Spaulding and Dr. C. Michael Gibson Discuss: SELUTION DeNovo:
Sirolimus-Eluting DCB vs. DES in De Novo Coronary Lesions View Video | View Slides

Dr. Donald Cutlip and Dr. C. Michael Gibson Discuss: SELUTION4ISR:
Sirolimus-Eluting DCB vs. DES or Balloon Angioplasty for In-Stent Restenosis View Video | View Slides

Dr. Suzanne J. Baron and Dr. C. Michael Gibson Discuss: Short-CUT:
Intravascular Lithotripsy vs. Cutting Balloon Angioplasty in Calcified CAD View Video

Dr. Matthias Bossard and Dr. C. Michael Gibson Discuss: VICTORY:
Intravascular Lithotripsy vs. Super-High-Pressure PTCA in Calcified and Refractory Coronary Lesions View Video | View Slides

Dr. Ruben de Winter and Dr. C. Michael Gibson Discuss: PROCTOR: Native Vessel vs. SVG PCI in Patients With Prior CABG View Video | View Slides

Dr. Shamir R. Mehta and Dr. C. Michael Gibson Discuss: STRIVE: Low-Dose r-tPA vs. Placebo in STEMI With Large Thrombus Burden View Video | View Slides

Dr. Robin Nijveldt and Dr. C. Michael Gibson Discuss: iMODERN:
iFR- vs. Cardiac MRI-Guided Revascularization of Non-Culprit Lesions in STEMI View Video | View Slides
This Week in Medicine

Dr. Marc Bonaca and Dr. C Michael Gibson discuss: When is the world ready for Asymptomatic CAD Screening? View Video

Dr. Danielle Belardo and Dr. C. Michael discuss: The Target is the Plaque: Stabilization, Regression, and the Role of Imaging and AI in Modern CAD Management View Video
HFSA 2025

Dr. Ahmad Masri and Dr. C. Michael Gibson discuss: Effect of Acoramidis on Recurrent and Cumulative Cardiovascular Outcomes in ATTR-CM: Exploratory Analysis from ATTRibute-CM View Video


Dr. Neal Lakdawala, Dr. Jim Januzzi and Dr. C. Michael Gibson discuss the findings were presented at HFSA from the phase 2a clinical trial of danicamtiv in patients with genetic DCM View Video
This Week in Medicine

Dr. Maros Ferencik and Dr. C. Michael Gibson discuss: Clinical Utility of Atherosclerosis Imaging in Symptomatic Patients: Lessons Learned from CCTA View Video
ESC 2025

Dr. Hofmann and Dr. Gibson discuss HELP-MI SWEDEHEART trial View Video | View Slides | View Slides

Dr. Renato Lopes and Dr. C. Michael Gibson discuss the results of the PARCUTE-HF trial testing the benefits of 2 drugs in a big but neglected population, those patients with Chagas Disease and Heart Failure View Video

Dr. Kevin Alexander and Dr. C. Michael Gibson discuss: Acoramidis reduces cardiovascular mortality (CVM): results at month 42 from the ATTRibute-CM open-label extension (OLE) study View Video

Dr. Dan Atar and Dr. C. Michael Gibson discuss the results of the BETAMI-DANBLOCk Trial of stopping Beta blockers after MI View Video

SMuRF-Less but inflamed: Dr Ridker and Dr. C. Michael Gibson discuss the high but modifiable risk of patients without Standard Modifiable Risk Factors who are inflamed View Video
This Week in Medicine

Dr. Alberto Morales and Dr. C. Michael Gibson discuss: Non-Invasive Atherosclerosis Evaluation: What Can We See and What are We Looking For? View Video

Dr. Daniel Chamie and Dr. C. Michael Gibson discuss: Clinical Utility of Atherosclerosis Imaging: Lessons Learned from Intravascular Ultrasound View Video

Dr. Leslee Shaw and Dr. C. Michael Gibson discuss the newly released DECIDE Registry primary endpoint. View Video

Dr. Nick Nurmohamed and Dr. C. Michael Gibson discuss: What We Thought Was Wrong: Evolution of the Approach to Evaluation and Treatment of Coronary Artery Disease Sponsored by Cleerly, Women as One, and International Atherosclerosis Society. View Video

Dr. Fatima Rodriguez and Dr. C. Michael Gibson discuss: Atherosclerosis: Basic Concepts and Current Understanding. Sponsored by Cleerly, Women as One, and International Atherosclerosis Society. View Video

Dr. Daniel Judge and Dr. C. Michael Gibson discuss data presented at ACC 2025: In Participants Treated with Acoramidis, Addition of Concomitant Tafamidis Did Not Further Increase Serum TTR Levels sponsored by BridgeBio Pharma, Inc. View Video

Dr. Rohan Khera and Dr. C. Michael Gibson discuss: Artificial Intelligence in cardiovascular care. Sponsored by BridgeBio Pharma, Inc. View Video

Dr. Daniel Judge and Dr. C. Michael Gibson discuss data presented at ACC 2025: Primary Endpoint Efficacy Results in The Attribute-CM Study: Pre-Specified Sensitivity Analyses Addressed Tafamidis Use. Sponsored by BridgeBio Pharma, Inc. View Video

Dr. Nitasha Sarswat and Dr. C. Michael Gibson discuss data presented at ACC 2025: Acoramidis-Mediated Early Increase in Serum Transthyretin Level Reduces Cardiovascular-Related Hospitalizations and Mortality: Insights From The Attribute-CM Study View Video

Dr. Brett Sperry and Dr. C. Michael Gibson discuss: Atrial fibrillation, arrythmias, and other cardiac manifestations in patients with ATTR-CM View Video

Dr. Ron Witteles and Dr. C. Michael Gibson discuss: Atrial fibrillation, arrythmias, and other cardiac manifestations in patients with ATTR-CM View Video

Dr. Richard Cheng and Dr. C. Michael Gibson discuss: Presentation, screening, and disease progression of variant ATTR-CM View Video

Dr. Kevin Alexander and Dr. C. Michael Gibson discuss data presented at ACC 2025: Dr. Kevin Alexander, Acoramidis Improves Serum TTR Levels in Patients with Wild-Type or Variant Transthyretin Amyloid Cardiomyopathy sponsored by BridgeBio Pharma, Inc. View Video

Dr. James Ampadu and Dr. C. Michael Gibson discuss: Transthyretin tetramer destabilization and increased mortality, and the physiologic importance of TTR. View Video

Dr. Richard Wright and Dr. C. Michael Gibson discuss: Transthyretin tetramer destabilization and increased mortality, and the physiologic importance of TTR. View Video

Dr. Joshua Mitchell and Dr. C. Michael Gibson discuss: Transthyretin tetramer destabilization and increased mortality, and the physiologic importance of TTR. View Video

Dr. M. Trejeeve Martyn and Dr. C. Michael Gibson discuss: The importance of early screening, diagnosis, and treatment for ATTR-CM View Video

Dr. Vaduganathan and Dr. C. Michael Gibson discuss the pivotal role of the MRA Axis in the treatment of heart failure and other chronic disease states. View Video

Dr. Adam Castano and Dr. C. Michael Gibson discuss: ACT-EARLY, a Phase 3 Study View Video

Dr. Shinya Goto and Dr. C. Michael Gibson discuss the vexing problem of antiplatelet and anticoagulant therapy in patients with hereditary clotting disorders like hemophilia. View Video

Dr. Gabriel Steg and Dr. C. Michael Gibson discuss the independent contribution of LDL, CRP and Lp(a) to cardiovascular risk including mortality. View Video

Dr. Sekar Kathiresan and Dr. C. Michael Gibson discuss “one and done” gene editing for high cholesterol by permanently inhibiting PCSK9 by about 70% to achieve an average LDL lowering of 59%. There were no safety signals in this early study. View Video Download Slides
ACC 2025

#ACC2025 Interventional Wrap Up: Dr. Merhran and Dr Gibson discuss the HOST-BR trial (optimal DAPT duration for high or low bleeding risk), ECLIPSE trial (orbital atherectomy vs. balloon angioplasty for calcified coronary lesions), BHF PROTECT-TAVI trial (cerebral embolic protection for stroke prevention after TAVI), FLAVOUR II trial (angioFFR vs. IVUS for guiding PCI), and ACC.25 experience. View Video

#SNACKABLEHEALTH with Gibson and Lam: Dr. Lam and I discuss the consistency of benefits with weight loss independent of GFR in the SUMMIT trial, IV iron for HFrEF with iron deficiency in the FAIR-HF2 trial, and gene therapy for HCM in the MyPEAK-1 study. View Video

#ACC2025 Obesity Wrap Up: Dr. Danielle Belardo and Dr. C. Michael Gibsob discuss the PRAGUE-25 trial (catheter ablation vs. antiarrhythmics with weight management and lifestyle alterations in AF), SOUL trial (oral semaglutide vs. placebo in DM with ASCVD/CKD), STRIDE trial (semaglutide vs. placebo in DM with PAD), EKSTROM trial (colchicine vs. placebo in stable CAD), and WARRIOR trial (intensive medical therapy vs. usual care in women with INOCA). View Video

#ACC2025 Antithrmbotic / Antiplatelet Wrap Up: Dr. Bhatt and Dr. C Michael Gibson discuss ticagrelor reversal using bentracimab from the REVERSE-IT trial, as well as comparable efficacy and safety of rivaroxaban vs. warfarin for post-MI LV thrombus from the RIVAWAR trial. View Video

Dr. Steven E. Nissen and Dr. C. Michael Gibson discuss: An Extended Duration Small-interfering RNA Targeting Lipoprotein(a): The Alpaca Phase 2 Trial Of Lepodisiran With 540 Day Follow Up View Video | View Slides

Dr. Pavel Osmancik and Dr. C. Michael Gibson discuss: Catheter Ablation Vs. Risk Factor Modification With Antiarrhythmic Drugs To Treat Atrial Fibrillation – PRAGUE-25 Study View Video | View Slides

Dr. Giulia Magnani and Dr. C. Michael Gibson discuss: Alliance For Secondary Prevention After An Acute Coronary Syndrome. View Video | View Slides

Dr. Xiaojie Xie and Dr. C. Michael Gibson discuss: Efficacy And Safety Of SHR-1918, An Angiopoietin-like 3 Monoclonal Antibody, In Combination With Lipid-lowering Therapy In Patients With Suboptimally Controlled Hyperlipidemia: A Multicenter, Randomized, Double Blind, Placebo-controlled Phase 2 Trial View Video | View Slides

Dr. Michael J. Koren and Dr. C. Michael Gibson discuss: Efficacy And Safety Of Azd0780, An Oral Small Molecule Pcsk9 Inhibitor For Treatment Of Hypercholesterolemia: Results From A Ph2b Randomized Placebo-controlled Clinical Trial View Video
Dr. Marco G. Mennuni and Dr. C. Michael Gibson discuss: Alternative Antithrombotic Pathways In Acute Myocardial Infarction With Large Thrombus Burden: A Randomized Trial ARISE-ARMYDA 7 View Video | View Slides

Dr. Marc Humbert and Dr. C. Michael Gibson discuss: Efficacy And Safety Of Sotatercept In High-Risk Patients With Pulmonary Arterial Hypertension: Results From ZENITH Phase 3 Trial View Video | View Slides

Dr. Kausik K. Ray and Dr. C. Michael Gibson discuss: Effect Of Solbinsiran, A Small Interfering RNA Targeting ANGPTL3, On Biomarkers Of Major Adverse Cardiovascular Events In Adults With Mixed Dyslipidemia: A Randomized Phase 2 Trial View Video | View Slides

Dr. Katja Vu Bartholdy and Dr. C. Michael Gibson discuss: Effects Of Dapagliflozin On Echocardiographic Measures Of Cardiac Structure And Function In Patients With Chronic Kidney Disease: The DECODE-CKD Trial View Video | View Slides

Dr. Matthew J. Budoff and Dr. C. Michael Gibson discuss: Effect Of Colchicine On Progression Of Known Coronary Atherosclerosis In Patients With Stable Coronary Artery Disease Compared To Placebo Ekstrom Trial View Video | View Slides

Dr. Saibal Kar and I discuss: Two-year Outcomes Of Transcatheter Tricuspid Valve Edge-to-edge Repair For Tricuspid Regurgitation: The Triluminate Pivotal Trial View Video | View Slides

Dr. Carolyn Hendrickson and Dr. C. Michael Gibson discuss: The Equiox Study: Evaluating Pulse Oximeter Bias Across A Range Of Skin Pigment In Critically Ill Adults View Video

Dr. Joo- Yong Hahn and Dr. C. Michael Gibson discuss: Clopidogrel Versus Aspirin For Long-term Maintenance Monotherapy In Patients With High Ischemic Risk After Percutaneous Coronary Intervention View Video | View Slides

Dr. William F. Fearon and Dr. C. Michael Gibson discuss: Fractional Flow Reserve Guided Percutaneous Coronary Intervention Compared With Bypass Surgery: Final 5 Year Results Of The Fractional Flow Reserve Versus Angiography For Multivessel Evaluation 3 Trial View Video | View Slides

Dr. Jian-An Wang and Dr. C. Michael Gibson discuss: Comparison Of Angiography-derived Fractional Flow Reserve-guided And Intravascular Ultrasound-guided Percutaneous Coronary Intervention Strategies: The FLAVOUR II Trial View Video

Dr. Michael J. Reardon and Dr. C. Michael Gibson discuss: 5-year Outcomes After Transcatheter Or Surgical Aortic Valve Replacement In Low-risk Patients With Aortic Stenosis View Video | View Slides

Dr. and Rajesh Kharbanda Dr. C. Michael Gibson discuss: Routine Cerebral Embolic Protection In Transcatheter Aortic Valve Implantation: The British Heart Foundation (BHF) PROTECT-TAVI Trial View Video | View Slides

Dr. Stefan D. Anker and Dr. C. Michael Gibson discuss: Ferric Carboxymaltose Assessment Of Morbidity And Mortality In Patients With Iron Deficiency And Chronic Heart Failure (FAIR-HF2) Trial View Video | View Slides

Dr. Roland Van Kimmenade and Dr. C. Michael Gibson discuss: Liberal Fluid Intake Versus Fluid Restriction In Chronic Heart Failure View Video | View Slides

Dr. Sergio Raposeiras Roubin and Dr. C. Michael Gibson Discuss: Dapagliflozin In Patients Undergoing Transcatheter Aortic Valve Implantantion View Video | View Slides

Dr. Antonius Buescher and Dr. C. Michael Gibson discuss: Development And External Validation Of A Deep Learning Electrocardiogram Model For Risk Stratification Of Coronary Revascularization Need In The Emergency Department View Video | View Slides

Dr. Hyo-Soo Kim and Dr. C. Michael Gibson discuss: Stratified Randomization Study To Compare Different Duration Of Dual Antiplatelet Therapy After Coronary Stenting In Either High Or Low Bleeding Risk Population. View Video | View Slides

Dr. Keyvan Karkouti and Dr. C. Michael Gibson discuss: Four-Factor Prothrombin Complex Concentrate Is Superior To Frozen Plasma In Bleeding Adult Cardiac Surgery Patients With Coagulopathy—Results From A Phase 3, Randomized, Active-Control Study. View Video | View Slides

Dr. Marc Bonaca and Dr. C. Michael Gibson discuss: The Effect Of Once-weekly Subcutaneous Semaglutide On Functional Capacity In People With Type 2 Diabetes And Peripheral Artery Disease: Primary Results From The Phase 3b, Randomized, Placebo-controlled, Double Blind Stride Trial. View Video | View Slides
This Week in Nephrology
Dr. Parikh and I discuss the definition and implementation of the Four Pillars of Care in patients with renal insufficiency. View Video
Dr. Parikh and I discuss exciting new developments Xenotransplantation for patients with renal insufficiency. View Video
This Week in Obesity

Participants randomized to the placebo arm in obesity trials often do not lose weight and as a result may drop out or may ask to be prescribed a commercially available obesity drug. Dr. Javed Butler and Dr. C. Michael Gibson discuss the challenges of using a placebo in obesity trials. View Video

Dr. C. Michael Gibson and Dr. Javed Butler discuss the flaws of BMI in obesity trials. View Video

Update on HFpEF and HFrEF obesity trials with Dr. Javed Butler. View Video

Dr. C. Michael Gibson and Dr. Perreault discuss the possibility or lack thereof that we can prevent and/or reverse diabetes and obesity. View Video

Dr. C. Michael Gibson and Dr. Perreault discuss the concept that there may or may not be an obesity set point throughout various stages of life. View Video

Dr. Gibson and Dr. Perreault discuss her PATHWEIGH study for pragmatic weight management in primary care. View Video


Dr. McGuire, Dr. Jastreboff, and Dr. C. Michael Gibson discuss best practices for titration of GLP-1 medications for optimal weight loss. View Video


Dr. McGuire, Dr. Jastreboff, and Dr. C. Michael Gibson explore the question of what is the right weight reduction for each patient taking GLP-1 medications? View Video


Dr. McGuire, Dr. Jastreboff, and Dr. C. Michael Gibson discuss the SUMMIT trial and how GLP-1 agonists may be a new pillar in the treatment for HFpEF and obesity. View Video


Dr. McGuire, Dr. Jastreboff, and Dr. C. Michael Gibson discuss new oral semaglutide and the SOUL trial which lowered death, MI and stroke rates by 14% in patients with diabetes. View Video


Dr. McGuire, Dr. Jastreboff, and Dr. C Michael Gibson discuss the SURMOUNT 1 Trial of Tirzepatide and how we may be able to diminish the progression from pre-diabetes to diabetes. View Video
This Week in Medicine

Drs. Wazni and Gibson do a deep dive on the results of the OPTION Trial answering many of the questions that have come up. View Video

von Willebrand factor molecules cross link and form a net around a blood clot holding it together. Drs. Shahid Nimjee and Gibson discuss a new vWf inhibitor that breaks apart this net & opening closed arteries but leaving a patch of fibrin strands across the site of plaque rupture which would have been dissolved by fibrinolytics potentially causing bleeding. View Video
